Make smarter decisions about your health.

The smallest kinds of genetic variation: a single DNA letter swapped for another, or a few letters inserted or deleted. These are what most "genetic tests" actually analyze, but most only look at a few hundred thousand pre-selected positions. We call and evaluate all ~5 million in your genome.

Bigger reshuffles of your DNA: chunks that got deleted, duplicated, flipped, or moved to a new location. Less common than single-letter changes, but they can span larger regions of the genome and affect multiple genes at once.

Places where you have more or fewer copies of a stretch of DNA than expected — extra copies of a region, or a region missing entirely. We report the location, size, and which genes fall within the affected region.

Some spots in the genome contain short DNA sequences that repeat over and over. In certain genes, expanded repeats are associated with conditions cataloged in clinical databases — including Huntington's, Fragile X, myotonic dystrophy, Friedreich's ataxia, and others. We count the repeats and report them alongside the published reference ranges.

About 20 genes are involved in how the body processes hundreds of common drugs, from antidepressants and blood thinners to painkillers and chemotherapy agents. We report the CPIC-classified metabolizer status for each gene, linked directly to the published guideline annotations.

HLA genes encode the proteins your immune system uses to recognize what belongs in your body and what doesn't. They are referenced in transplant databases, pharmacogenomic guidelines, and published disease-association studies. We identify your HLA alleles at full typing resolution.

Your mitochondria, the energy-producing compartments inside your cells, carry their own small, circular genome, inherited from your mother. We identify variants across it and report them alongside the rest of your DNA, with a note that mtDNA behaves differently: you have many copies per cell, and not all of them necessarily carry the same variant.

Where your DNA traces back to, estimated by comparing your genome to reference populations from around the world. Ancestry composition is also used as a reference input when calculating polygenic scores from the PGS Catalog.

For many common traits and conditions, published research has identified thousands of tiny variants across the genome that collectively contribute to a polygenic score. We calculate these scores using models from the PGS Catalog, the published registry of polygenic scores reported with their performance metrics. Adjusted for ancestry composition where possible.